The PRISMA Statement (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) is an internationally recognized reporting guideline developed to improve the quality, transparency, clarity, and completeness of Systematic Reviews and Meta-Analyses. PRISMA is considered one of the most important methodological standards in evidence-based medicine and is widely required by scientific journals when submitting Systematic Reviews for publication. Its primary purpose is to ensure that researchers report all essential methodological and analytical details in a structured and reproducible manner, allowing readers, reviewers, and clinicians to fully understand how the review was conducted and how the final conclusions were reached.

PRISMA is mainly used for:

• Systematic Reviews
• Meta-Analyses
• Evidence synthesis studies
• Reviews involving randomized and non-randomized studies

The PRISMA guideline consists mainly of two important components:

1. The PRISMA Checklist
2. The PRISMA Flow Diagram

Although they are closely related, they serve different purposes.

PRISMA Checklist

The PRISMA checklist is a structured reporting document containing all essential items that should be described within the manuscript. It helps ensure that the review is scientifically complete and transparently reported. The checklist covers multiple sections of the manuscript, including:

• title,
• abstract,
• introduction,
• methodology,
• literature search,
• study selection,
• risk of bias,
• statistical analysis,