What is a Case Report?

A Clinical Research Case Report is a descriptive scientific study that presents detailed information about a single patient with:

• A rare disease
• An unusual presentation
• A novel treatment
• An unexpected complication
• A unique diagnostic challenge
• A rare adverse event
• An uncommon clinical association

Case Reports are among the oldest forms of medical literature and are highly important for:

• Medical education
• Hypothesis generation
• Recognition of new diseases
• Detection of adverse events
• Improving clinical awareness

Although Case Reports are considered low in the hierarchy of evidence, they may significantly influence future research and clinical practice when the reported findings are highly novel or clinically important.

What is a Case Series?

A Clinical Research Case Series is a descriptive study involving multiple patients with similar:

• Diseases
• Clinical findings